Structure
| TCI Product No. : | T0133 | |||||||||
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| Stock Status : |
Status at 03:00 a.m. on Feb 09, 2012 (IST) * Items available from stock in Japan will be delivered in 7 business days |
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| Purity / Analysis Method : | ||||||||||
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| M.F. / M.W. : | C12H28O4Ti=284.22 | |||||||||
| CAS Number : | 546-68-9 | |||||||||
| Related CAS Number : | ||||||||||
| MDL Number : | MFCD00008871 |
| fp : | 18 °C |
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| d : | 0.97 |
Reductive Amination Typical Procedure: To the solution of carbonyl compound (1 mmol) in THF (4 mL), the primary or secondary amine (1.2 mmol) is added followed by the addition of Ti(Oi-Pr)4 (1.2 mmol). The reaction mixture is stirred for 1 h at room temperature. Ammonia borane (1.2 mmol) is added and stirring is continued at the same temperature. Upon completion of the reaction, as revealed by TLC, the resulting mixture is treated with HCl (3 mL, 6 M) and stirred for an additional hour. The reaction mixture is diluted with water (10 mL) and extracted with diethyl ether (3 × 15mL). The aqueous layer is then treated with NaOH (2 M) until pH 10-12 and extracted with diethyl ether (3 × 15mL). The combined organic extracts are washed with brine, dried (Na2SO4), concentrated in vacuo, and purified by silica gel flash chromatography to obtain the desired product. |
| Beilstein : | 1(2)382 |
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| Merck Index(14) : | 9480 |
| F & F : | 10, 404 |
| RTECS# : | NT8060000 |
| UNNo. : | 2413 |
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| Class : | 3 |
| PG : | III |
| Related Categories : |
Structure of Chemicals
Classes of Metal Compounds
Transition Metal Compounds
Ti (Titanium) Compounds
Synthetic Organic Chemistry Catalysts for Organic Synthesis Homogeneous Catalysts Titanium Synthetic Organic Chemistry Catalysts for Organic Synthesis Homogeneous Catalysts Titanium Alkoxides, etc. (Homogeneous Catalysts) |
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