Structure
| TCI Product No. : | B0527 | ||||||||||||
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| Stock Status : |
Status at 03:00 a.m. on Feb 09, 2012 (IST) * Items available from stock in Japan will be delivered in 7 business days |
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| Purity / Analysis Method : | >98.0%(W) | ||||||||||||
| Storage : | |||||||||||||
| M.F. / M.W. : | BF3.C4H10O=141.93 | ||||||||||||
| CAS Number : | 109-63-7 | ||||||||||||
| Related CAS Number : | |||||||||||||
| MDL Number : | MFCD00013194 |
| bp : | 124 °C |
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| d : | 1.13 |
Stereoselective ring-opening hydrofluorination of aryl epoxides Typical procedure: (RS,RS)-2-Methyl-3-phenyloxirane (4.5 g), BF3• OEt2 (1.38 mL) and CH2Cl2 (134 mL) were reacted at 20 ºC for 5 min. Saturated aqueous NaHCO3 was then added and the mixture was stirred vigorously until both layers became clear. The layers were separated and the organic phase was washed with sat. aq. NaHCO3. The combined aqueous phases were extracted twice with CH2Cl2 and the combined organic extracts were dried and concentrated in vacuo. The residue was purified by flash column chromatography (gradient elution, 5 % to 40 % EtOAc in 30~40 ºC petrol) gave (RS,RS)-1-fluoro-1-phenylpropane-2-ol as a colorless oil (4.31 g, 83 %, more than 99:1 dr). |
| Merck Index(14) : | 1350 |
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| F & F : | 9, 64 |
| UNNo. : | 2604 |
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| Class : | 8 / 3 |
| PG : | I |
| Related Categories : |
Synthetic Organic Chemistry
Glycosylation
Activating Agents (Glycosylation)
Structure of Chemicals B (Classes of Boron Compounds) Boron Trihalides Boron Trifluorides Synthetic Organic Chemistry Carbonyl Olefination Titanium-mediated Carbonyl Olefination Others (Titanium-mediated Carbonyl Olefination) Analytical Chemistry NMR Spectrometry Chemical Shift Standards for Multinuclear NMR Biochemistry Sugars Reagents for Oligosaccharide Synthesis |
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